Immobilized ACE-2 Fc Chimera, Human (Cat. No. Z03484) at 2 μg/mL can bind SARS-CoV-2 Spike protein (ECD, His & Flag Tag) (Cat. No. Z03481) with a serial dilution.
THETM His Tag Antibody [HRP], mAb, Mouse(Cat.No.A00612) is used as a secondary antibody (0.1 μg/mL).
Lane 1: 1μg of SARS-CoV-2 Spike protein (ECD, His & Flag Tag), reducing(R)
> 95% as analyzed by SDS-PAGE
SARS-CoV-2 Spike protein (ECD, His & Flag Tag)
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. SARS-CoV-2 Spike Protein is composed of S1 domain and S2 domain. S1 contains a receptor-binding domain (RBD) that can specifically bind to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells. ECD is the extra cellular domain of spike protein.
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