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α-Factor Mating Pheromone, yeast

The alpha factor pheromone arrests yeast in the G1 phase of their cell cycle. Alpha Factor Mating Pheromone induces the expression of mating genes, changes in nuclear architecture, and polarzes growth toward the mating partner. STE2 encodes the alpha factor pheromone receptor (a GPCR) found on mating-type-A cells in yeast.
¥1200
RP01002

Synonyms pheromone moth; mating animals
Description The alpha factor pheromone arrests yeast in the G1 phase of their cell cycle. Alpha Factor Mating Pheromone induces the expression of mating genes, changes in nuclear architecture, and polarzes growth toward the mating partner. STE2 encodes the alpha factor pheromone receptor (a GPCR) found on mating-type-A cells in yeast.
Cas No 59401-28-4
Sequence
{TRP}{HIS}{TRP}{LEU}{GLN}{LEU}{LYS}{PRO}{GLY}{GLN}{PRO}{MET}
{TYR}
Sequence Shortening WHWLQLKPGQPMY
Molecular Formula C82H114N20O17S
Molecular Weight 1683.98
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Purity > 95%
Solubility Soluble in Ultrapure water under 1mg/ml
Form Lyophilized
Storage Store this peptide in its dry form at -20°C. For best results, rehydrate the peptide immediately before use. Do not re-freeze any unused portions.
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Michal Chappleboim, et al. Ordered and disordered regions of the Origin Recognition Complex direct differential in vivo binding at distinct motif sequences. Nucleic Acids Res. (2024-06)
Jingrong Chen, et al. Cornelia de Lange Syndrome mutations in SMC1A cause cohesion defects in yeast. Genetics. (2023-10)
Federico Zucca, et al. APC/CCdc20-mediated degradation of Clb4 prompts astral microtubule stabilization at anaphase onset. J Cell Biol. (2022-10)
Mercè Gomar-Alba, et al. Nuclear pore complex acetylation regulates mRNA export and cell cycle commitment in budding yeast. EMBO J. (2022-06)
Ruggiero A, et al. The Phosphatase PP1 Promotes Mitotic Slippage through Mad3 Dephosphorylation. Curr Biol. (2020)
Leutert M, et al. R2-P2 rapid-robotic phosphoproteomics enables multidimensional cell signaling studies. Molecular systems biology. (2019-12)
Zapatka M, et al. Sumoylation of Smc5 Promotes Error-free Bypass at Damaged Replication Forks. Cell Rep. (2019)
Álvarez V, et al. PCNA Deubiquitylases Control DNA Damage Bypass at Replication Forks. Cell Rep. (2019)
Oh Julyun, et al. Xrs2 and Tel1 Independently Contribute to MR-Mediated DNA Tethering and Replisome Stability. Cell Rep. (2018)
Kruitwagen T, et al. Centromeres License the Mitotic Condensation of Yeast Chromosome Arms. Cell. (2018)
LiYang, et al. Mitogen-activated protein kinase (MAPK) dynamics determine cell fate in the yeast mating response. J. Biol. Chem. (2017-12)
Ly Nina, et al. Calcineurin, the Ca-dependent phosphatase, regulates Rga2, a Cdc42 GTPase-activating protein, to modulate pheromone signaling. Mol. Biol. Cell. (2017)
MishraPrashant K, et al. Pat1 protects centromere-specific histone H3 variant Cse4 from Psh1-mediated ubiquitination. Mol. Biol. Cell. (2015-06)
Lickwar CR, et al. Genome-wide measurement of protein-DNA binding dynamics using competition ChIP. Nat Protoc. (2013-06)
Boeckmann L, et al. Phosphorylation of centromeric histone H3 variant regulates chromosome segregation in S. cerevisiae. Mol Biol Cell. (2013-05)
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