Human MTR Antibody (11G1D7), mAb, Mouse

MTR encodes the 5-methyltetrahydrofolate-homocysteine methyltransferase, which is also known as cobalamin-dependent methionine synthase, catalyzes the final step in methionine biosynthesis. Mutations in MTR have been identified as the underlying cause of methylcobalamin deficiency complementation group G. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Among its related pathways are Metabolism and Cytochrome P450-arranged by substrate type. Catalyzing the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I) alamin and methionine. Subsequently, remethylating the cofactor using methyltetrahydrofolate. KO Validated GenScript Human MTR Antibody (11G1D7), mAb, Mouse is produced from a hybridoma resulting from the fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse immunized with recombinant human MTR.