GPR30 Antibody, pAb, Rabbit

该产品已下架。

GPR30 (G Protein-coupled Receptor 30), also known as G Protein-coupled estrogen Receptor 1 (GPER), is a member of G protein-coupled receptor family. It contains seven hydrophobic transmembrane domains embedded in hydrophilic intra- and extracellular loops. GPR30 transduces a variety of hormone, endogenous peptide, and neurotransmitter signals into intracellular effects via G proteins. GPR30 is an orphan receptor and localizes to the endoplasmic reticulum, where it specifically binds estrogen and estrogen derivatives. Activating GPR30 via estrogen results in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. GenScript Rabbit Anti-GPR30 Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide from amino terminal of human GPR30 protein (Swiss Prot: Q99527).

产品编号	A01074
规格	定制报价

联系我们

产品概述

Specificity	GenScript Rabbit Anti-GPR30 Polyclonal Antibody detects endogenous levels of human GPR30 protein.
Host Species	Rabbit
Immunogen	KLH-coupled synthetic peptide from amino terminal of human GPR30 protein (Swiss Prot: Q99527)
Species Reactivity	Human

应用指导

Application	Recommended Usage
ELISA	0.05-0.2 µg/ml
Western Blot	0.5-1.0 µg/ml
IHC	5-10 µg/ml
Other applications	User-optimized

产品属性

Concentration	0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide
Reconstitution	Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.
Purification	Immunoaffinity chromatography

技术背景

Target Background

GPR30 (G Protein-coupled Receptor 30), also known as G Protein-coupled estrogen Receptor 1 (GPER), is a member of G protein-coupled receptor family. It contains seven hydrophobic transmembrane domains embedded in hydrophilic intra- and extracellular loops. GPR30 transduces a variety of hormone, endogenous peptide, and neurotransmitter signals into intracellular effects via G proteins. GPR30 is an orphan receptor and localizes to the endoplasmic reticulum, where it specifically binds estrogen and estrogen derivatives. Activating GPR30 via estrogen results in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus.
GenScript Rabbit Anti-GPR30 Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide from amino terminal of human GPR30 protein (Swiss Prot: Q99527).

Synonyms

Rabbit Anti-GPR30 NT pAb;