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HTRA1 disaggregates α-synuclein amyloid fibrils and converts them into non-toxic and seeding incompetent species
Authors: Sheng Chen, Anuradhika Puri, Braxton Bell, Joseph Fritsche, Hector H Palacios, Maurie Balch, Macy L Sprunger, Matthew K Howard, Jeremy J Ryan, Jessica N Haines, Gary J Patti, Albert A Davis, Meredith E Jackrel
Journal: Nat Commun
PubMed ID: 38499535
Doi: 10.1038/s41467-024-46538-8
Products & Services: Molecular Biology Reagents   
Novel Fragment Inhibitors of PYCR1 from Docking-Guided X-ray Crystallography
Authors: Kaylen R Meeks, Juan Ji , Mykola V Protopopov , Olga O Tarkhanova , Yurii S Moroz , John J Tanner
Journal: J Chem Inf Model
PubMed ID: 38411104
Doi: 10.1021/acs.jcim.3c01879
Products & Services: Molecular Biology Reagents   
Complex -glycans are important for interspecies transmission of H7 influenza A viruses
Authors: Cindy M Spruit, Diana I Palme, Tiehai Li, María Ríos Carrasco, Alba Gabarroca García, Igor R Sweet, Maryna Kuryshko, Joshua C L Maliepaard, Karli R Reiding, David Scheibner, Geert-Jan Boons, Elsayed M Abdelwhab, Robert P de Vries
Journal: J Virol
PubMed ID: 38470143
Doi: 10.1128/jvi.01941-23
Products & Services: PCR Cloning and Subcloning   
Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1
Authors: Xiong Xie, Qiaoshuai Lan, Jinyi Zhao, Sulin Zhang, Lu Liu, Yumin Zhang, Wei Xu, Maolin Shao, Jingjing Peng, Shuai Xia, Yan Zhu, Keke Zhang, Xianglei Zhang, Ruxue Zhang, Jian Li, Wenhao Dai, Zhen Ge, Shulei Hu, Changyue Yu, Jiang Wang, Dakota Ma, Mingyue Zheng, Haitao Yang, Gengfu Xiao, Zihe Rao, Lu Lu, Leike Zhang, Fang Bai, Yao Zhao, Shibo Jiang, Hong Liu
Journal: Signal Transduct Target Ther
PubMed ID: 38443334
Doi: 10.1038/s41392-024-01758-8
Products & Services: Custom DNA/RNA Oligos   
Evaluating microcystinase A-based approach on microcystins degradation during harvested cyanobacterial blooms
Authors: Siyu Yang, Jun Zuo, Hans-Peter Grossart, Guofei Dai, Jin Liu, Lirong Song, Nanqin Gan
Journal: Environ Pollut
PubMed ID: 38548158
Doi: 10.1016/j.envpol.2024.123878
Products & Services: Molecular Biology Reagents   
Expression and functional analysis of a recombinant aquaporin Z from Antarctic Pseudomonas sp AMS3
Authors: S Balakrishnan, R N Z R A Rahman, N D M Noor, W Latip, M S M Ali
Journal: Proteins
PubMed ID: 38477414
Doi: 10.1002/prot.26680
Products & Services: Molecular Biology Reagents   
Molecular basis of TMPRSS2 recognition by Paeniclostridium sordellii hemorrhagic toxin
Authors: Ruoyu Zhou, Liuqing He, Jiahao Zhang, Xiaofeng Zhang, Yanyan Li, Xiechao Zhan, Liang Tao
Journal: Nat Commun
PubMed ID: 38438396
Doi: 10.1038/s41467-024-46394-6
Products & Services: Codon Optimization   
Targeting deoxynivalenol for degradation by a chimeric manganese peroxidase/glutathione system
Authors: Xiaoyun Su, Shuai Wang, Xiaolu Wang, Wangli Ji, Honglian Zhang, Tao Tu, Nina Hakulinen, Huiying Luo, Wei Zhang, Huoqing Huang
Journal: Ecotoxicol Environ Saf
PubMed ID: 38394761
Doi: 10.1016/j.ecoenv.2024.116130
Enhancing sensitivity of qPCR assays targeting Streptococcus pneumoniae, Neisseria meningitidis and Haemophilus influenzae by using a mutant Taq DNA polymerase
Authors: Selin Nar Otgun, Canan Zohre Ketre Kolukirik, Nuriye Unal Sahin, Mustafa Kolukirik, Gozde Girgin Ozgumus, Meral Turan, Mert Elmas, Selcuk Kilic
Journal: J Microbiol Methods
PubMed ID: 38360298
Doi: 10.1016/j.mimet.2024.106899
Products & Services: Gene Synthesis   
Disordered regions mediate the interaction of p53 and MRE11
Authors: Sinem Usluer , Markus Galhuber , Yukti Khanna , Benjamin Bourgeois , Emil Spreitzer , Helene Michenthaler, Andreas Prokesch, Tobias Madl
Journal: Cell Research
PubMed ID: 38123020
Doi: 10.1016/j.bbamcr.2023.119654
Products & Services: Custom Vector Construction