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Identification of a novel ALDH1A3-selective inhibitor by a chemical probe with unrelated bioactivity: An approach to affinity-based drug target discovery
Authors: Hiroshi Kamiyama, Masayuki Miyano, Daisuke Ito, Takayuki Kimura, Koji Hagiwara, Hiroyuki Kogai, Yosuke Kaburagi, Yoshihiko Kotake, Yasutaka Takase
Journal: Chem Biol Drug Des
PubMed ID: 36334047
Doi: 10.1111/cbdd.14176
Products & Services: Plasmid DNA Preparation   
Structure-based engineering of minimal Proline dehydrogenase domains for inhibitor discovery
Authors: Alexandra N Bogner, Juan Ji, John J Tanner
Journal: Protein Eng Des Sel
PubMed ID: 36448708
Doi: 10.1093/protein/gzac016
Products & Services: Plasmids for SARS-CoV-2 Detection and Research   
De novo design of anti-tuberculosis agents using a structure-based deep learning method
Authors: Sowmya Ramaswamy Krishnan, Navneet Bung, Siladitya Padhi, Gopalakrishnan Bulusu, Parimal Misra, Manojit Pal, Srinivas Oruganti, Rajgopal Srinivasan, Arijit Roy
Journal: J Mol Graph Model
PubMed ID: 36257148
Doi: 10.1016/j.jmgm.2022.108361
Products & Services: Plasmid DNA Preparation   
Proline-Rich Region II (PRR2) Plays an Important Role in Tau-Glycan Interaction: An NMR Study
Authors: Anqesha Murray, Lufeng Yan, James M Gibson, Jian Liu, David Eliezer, Guy Lippens, Fuming Zhang, Robert J Linhardt, Jing Zhao, Chunyu Wang
Journal: Biomolecules
PubMed ID: 36358923
Doi: 10.3390/biom12111573
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Development and in vitro characterization of a humanized scFv against fungal infections
Authors: Tomas Di Mambro, Tania Vanzolini, Marzia Bianchi, Rita Crinelli, Barbara Canonico, Filippo Tasini, Michele Menotta, Mauro Magnani
Journal: PLoS ONE
PubMed ID: 36315567
Doi: 10.1371/journal.pone.0276786
Products & Services: Bacterial Expression   
Glycoside hydrolase subfamily GH5_57 features a highly redesigned catalytic interface to process complex hetero-β-mannans
Authors: Marcele P Martins, Mariana A B Morais, Gabriela F Persinoti, Rafael H Galinari, Li Yu, Yoshihisa Yoshimi, Fernanda B Passos Nunes, Tatiani B Lima, Shayla F Barbieri, Joana L M Silveira, Vincent Lombard, Nicolas Terrapon, Paul Dupree, Bernard Henrissat, Mário T Murakami
Journal: Acta Crystallogr D Struct Biol
PubMed ID: 36322419
Doi: 10.1107/S2059798322009561
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Reverse genetics based H5N2 vaccine provides clinical protection against H5N1, H5N8 and H9N2 avian influenza infection in chickens
Authors: Sivasankar Panickan, Sandeep Bhatia, Sushant Bhat, Nisha Bhandari, Atul Kumar Pateriya, Semmannan Kalaiyarasu, Richa Sood, Meghna Tripathi
Journal: Vaccine
PubMed ID: 36374710
Doi: 10.1016/j.vaccine.2022.10.018
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Lysyl-tRNA synthetase, a target for urgently needed M tuberculosis drugs
Authors: Simon R Green, Susan H Davis, Sebastian Damerow, Curtis A Engelhart, Michael Mathieson, Beatriz Baragaña, David A Robinson, Jevgenia Tamjar, Alice Dawson, Fabio K Tamaki, Kirsteen I Buchanan, John Post, Karen Dowers, Sharon M Shepherd, Chimed Jansen, Fabio Zuccotto, Ian H Gilbert, Ola Epemolu, Jennifer Riley, Laste Stojanovski, Maria Osuna-Cabello, Esther Pérez-Herrán, María José Rebollo, Laura Guijarro López, Patricia Casado Castro, Isabel Camino, Heather C Kim, James M Bean, Navid Nahiyaan, Kyu Y Rhee, Qinglan Wang, Vee Y Tan, Helena I M Boshoff, Paul J Converse, Si-Yang Li, Yong S Chang, Nader Fotouhi, Anna M Upton, Eric L Nuermberger, Dirk Schnappinger, Kevin D Read, Lourdes Encinas, Robert H Bates, Paul G Wyatt, Laura A T Cleghorn
Journal: Nat Commun
PubMed ID: 36220877
Doi: 10.1038/s41467-022-33736-5
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Nuclear Factor Kappa B Promotes Ferritin Heavy Chain Expression in in Response to Nucleopolyhedrovirus Infection
Authors: Linbao Zhu, Yingxue Liu, Ancheng Wang, Xiya Chen, Handan Zhu, Zhihao Huang, Huihua Cao, Shihuo Liu, Jiaping Xu
Journal: Int J Mol Sci
PubMed ID: 36142290
Doi: 10.3390/ijms231810380
Products & Services: Recombinant Antibody Expression   
Simple and practical sialoglycan encoding system reveals vast diversity in nature and identifies a universal sialoglycan-recognizing probe derived from AB5 toxin B subunits
Authors: Aniruddha Sasmal, Naazneen Khan, Zahra Khedri, Benjamin P Kellman, Saurabh Srivastava, Andrea Verhagen, Hai Yu, Anders Bech Bruntse, Sandra Diaz, Nissi Varki, Travis Beddoe, Adrienne W Paton, James C Paton, Xi Chen, Nathan E Lewis, Ajit Varki
Journal: Glycobiology
PubMed ID: 36048714
Doi: 10.1093/glycob/cwac057
Products & Services: ORF cDNA Clones/MolecularCloud