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Memory Impairment Induced by Borna Disease Virus 1 Infection is Associated with Reduced H3K9 Acetylation.

Cell. Physiol. Biochem.. 2018; 
JieJie，XuXiaoyan，XiaJinjun，TuZhe，GuoYujie，LiChenmeng，ZhangXiong，WangHaiyang，SongWeihong，Xie
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Monoclonal Antibody Services … Cells were then incubated for 12h with anti-BoDV-1-specific p24 and p40 protein primary monoclonal antibody (1: 200; GenScript, Nanjing, China) or anti-MAP2 antibody (1: 2000; Abcam, Cambridge, UK) at 4°C, followed by incubation with secondary antibodies for 2 h at room … Get A Quote

摘要

Borna disease virus 1 (BoDV-1) infection induces cognitive impairment in rodents. Emerging evidence has demonstrated that Chromatin remodeling through histone acetylation can regulate cognitive function. In the present study， we investigated the epigenetic regulation of chromatin that underlies BoDV-1-induced cognitive changes in the hippocampus.

关键词

Borna Disease Virus 1，H3K9 acetylation，Memory impairment，Synaptic plasti
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