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PIEZO1 loss-of-function compound heterozygous mutations in the rare congenital human disorder Prune Belly Syndrome
Authors: Nathalia G Amado , Elena D Nosyreva , David Thompson , Thomas J Egeland , Osita W Ogujiofor , Michelle Yang , Alexandria N Fusco , Niccolo Passoni , Jeremy Mathews , Brandi Cantarel , Linda A Baker , Ruhma Syeda
Journal: Nat Commun
PubMed ID: 38184690
Doi: 10.1038/s41467-023-44594-0
Products & Services: PCR Cloning and Subcloning   
A stapled lipopeptide platform for preventing and treating highly pathogenic viruses of pandemic potential
Authors: Gregory H Bird , J J Patten , William Zavadoski , Nicole Barucci , Marina Godes , Benjamin M Moyer , Callum D Owen , Paul DaSilva-Jardine , Donna S Neuberg , Richard A Bowen , Robert A Davey , Loren D Walensky
Journal: Nat Commun
PubMed ID: 38177138
Doi: 10.1038/s41467-023-44361-1
Products & Services: Plasmid DNA Preparation   
Massively parallel profiling of RNA-targeting CRISPR-Cas13d
Authors: Hung-Che Kuo , Joshua Prupes , Chia-Wei Chou , Ilya J Finkelstein
Journal: Nat Commun
PubMed ID: 37034598
Doi: 10.1101/2023.03.27.534188
Products & Services: Custom Vector Construction   
9S1R nullomer peptide induces mitochondrial pathology, metabolic suppression, and enhanced immune cell infiltration, in triple-negative breast cancer mouse model
Authors: Nilufar Ali, Cody Wolf, Swarna Kanchan, Shivakumar R Veerabhadraiah, Laura Bond, Matthew W Turner, Cheryl L Jorcyk, Greg Hampikian
Journal: Biomed Pharmacother
PubMed ID: 38118350
Doi: 10.1016/j.biopha.2023.115997.
Products & Services: Peptide Synthesis   
N-acetyltransferase 10 regulates alphavirus replication via N4- acetylcytidine (ac4C) modification of the lymphocyte antigen six family member E (LY6E) mRNA
Authors: Yamei Dang , Jia Li , Yuchang Li , Yuan Wang , Yajing Zhao , Ningbo Zhao , Wanying Li , Hui Zhang , Chuantao Ye , Hongwei Ma , Liang Zhang , He Liu , Yangchao Dong , Min Yao , Yingfeng Lei , Zhikai Xu , Fanglin Zhang , Wei Ye
Journal: J Virol .
PubMed ID: 38169284
Doi: 10.1128/jvi.01350-23
Products & Services: Polyclonal Antibody Services   
Guiding bar motif of thioredoxin reductase 1 modulates enzymatic activity and inhibitor binding by communicating with the co-factor FAD and regulating the flexible C-terminal redox motif
Authors: Wuyang Shi , Shibo Sun , Haowen Liu , Yao Meng , Kangshuai Ren , Guoying Wang , Minghui Liu , Jiaqi Wu , Yue Zhang , Huang Huang , Meiyun Shi , Weiping Xu , Qiang Ma , Bingbing Sun , Jianqiang Xu
Journal: Redox biology
Doi: 10.1016/j.redox.2024.103050
Products & Services: Proteins, Expression, Isolation and Analysis   
Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines
Authors: Gisele Nishiguchi , Lauren G Mascibroda , Sarah M Young , Elizabeth A Caine , Sherif Abdelhamed , Jeffrey J Kooijman , Darcie J Miller , Sourav Das , Kevin McGowan , Anand Mayasundari , Zhe Shi , Juan M Barajas , Ryan Hiltenbrand , Anup Aggarwal , Yunchao Chang , Vibhor Mishra , Shilpa Narina , Melvin Thomas , Allister J Loughran , Ravi Kalathur , Kaiwen Yu , Suiping Zhou , Xusheng Wang , Anthony A High , Junmin Peng , Shondra M Pruett-Miller , Danette L Daniels , Marjeta Urh , Anang A Shelat , Charles G Mullighan , Kristin M Riching , Guido J R Zaman , Marcus Fischer , Jeffery M Klco , Zoran Rankovic
Journal: Nat Commun
PubMed ID: 38228616
Doi: 10.1038/s41467-024-44698-1
Products & Services: Custom Vector Construction   
Repeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting
Authors: Ayijiang Yisimayi, Weiliang Song, Jing Wang, Fanchong Jian, Yuanling Yu, Xiaosu Chen, Yanli Xu, Sijie Yang, Xiao Niu, Tianhe Xiao, Jing Wang , Lijuan Zhao, Haiyan Sun, Ran An, Na Zhang, Yao Wang, Peng Wang, Lingling Yu, Zhe Lv, Qingqing Gu, Fei Shao, Ronghua Jin, Zhongyang Shen, Xiaoliang Sunney Xie, Youchun Wang, Yunlong Cao
Journal: Nature
PubMed ID: 37993710
Doi: 10.1038/s41586-023-06753-7
Products & Services: Gene Synthesis   
Structural basis of Gabija anti-phage defence and viral immune evasion
Authors: Sadie P Antine, Alex G Johnson, Sarah E Mooney, Azita Leavitt, Megan L Mayer, Erez Yirmiya, Gil Amitai, Rotem Sorek, Philip J Kranzusch
Journal: Nature
PubMed ID: 37992757
Doi: 10.1038/s41586-023-06855-2
Products & Services: Gene Synthesis   
A synthetic differentiation circuit in Escherichia coli for suppressing mutant takeover
Authors: David S Glass 1, Anat Bren 2, Elizabeth Vaisbourd 2, Avi Mayo 2, Uri Alon
Journal: Cell
PubMed ID: 38320549
Doi: 10.1016/j.cell.2024.01.024
Products & Services: Plasmid DNA Preparation   

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