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Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes

Authors: Zebin Tong , Huasong Ai, Ziyu Xu , Kezhang He , Guo-Chao Chu, Qiang Shi , Zhiheng Deng, Qiaomei Xue , Maoshen Sun, Yunxiang Du , Lujun Liang, Jia-Bin Li , Man Pan , Lei Liu

Journal: Nat Struct Mol Biol .

PubMed ID: 38177667

Doi: 10.1038/s41594-023-01141-1

Products & Services: Proteins, Expression, Isolation and Analysis Gene Synthesis

Inhaled nanoparticles for treating idiopathic pulmonary fibrosis by inhibiting honeycomb cyst and alveoli interstitium remodeling

Authors: Meng-Meng Han , Ling Tang , Bin Huang , Xue-Na Li , Yue-Fei Fang , Liang Qi , Bo-Wen Duan , Ya-Ting Yao , Yu-Jing He , Lei Xing , Hu-Lin Jiang

Journal: J Control Release .

PubMed ID: 38242209

Doi: 10.1016/j.jconrel.2024.01.032

Products & Services: Catalog Antibody

Regulation of RAS palmitoyltransferases by accessory proteins and palmitoylation

Authors: Anlan Yang , Shengjie Liu , Yuqi Zhang , Jia Chen , Yujing Fan , Fengxiang Wang , Yilong Zou , Shan Feng , Jianping Wu , Qi Hu

Journal: Nat Struct Mol Biol .

PubMed ID: 38182928

Doi: 10.1038/s41594-023-01183-5

Products & Services: Proteins, Expression, Isolation and Analysis

Disordered-to-ordered transitions in assembly factors allow the complex II catalytic subunit to switch binding partners

Authors: Pankaj Sharma, Elena Maklashina, Markus Voehler, Sona Balintova , Sarka Dvorakova, Michal Kraus, Katerina Hadrava Vanova Zuzana Nahacka, Renata Zobalova, Stepana Boukalova, Kristyna Cunatova, Tomas Mracek, Hans K Ghayee, Karel Pacak, Jakub Rohlena, Jiri Neuzil, Gary Cecchini,T M Iverson

Journal: Nat Commun

PubMed ID: 38212624

Doi: 10.1038/s41467-023-44563-7

Products & Services: Gene Synthesis

MARS an improved de novo peptide candidate selection method for non-canonical antigen target discovery in cancer

Authors: Hanqing Liao , Carolina Barra , Zhicheng Zhou , Xu Peng , Isaac Woodhouse , Arun Tailor , Robert Parker , Alexia Carré , Persephone Borrow , Michael J Hogan , Wayne Paes , Laurence C Eisenlohr , Roberto Mallone , Morten Nielsen , Nicola Ternette

Journal: Nat Commun

PubMed ID: 38253617

Doi: 10.1038/s41467-023-44460-z

Products & Services: Peptide Synthesis

The role of CD38 in inflammation-induced depression-like behavior and the antidepressant effect of (R)-ketamine

Authors: Xinying Zhang a , Teng He a , Zifeng Wu a , Yuanyuan Wang a, Hanyu Liu a, Bingyuan Zhang a, Siqi Yang a, Di Wang a, Chaoli Huang a, Jiahao Duan b, Xiangyang Xu c, Xiangqing Xu c, Kenji Hashimoto d, Riyue Jiang e, Ling Yang b, Chun Yang

Journal: Brain, behavior, and immunity

PubMed ID: 37793489

Doi: 10.1016/j.bbi.2023.09.026

Products & Services: Gene Synthesis

Acylspermidines are conserved mitochondrial sirtuin-dependent metabolites

Authors: Bingsen Zhang, James Mullmann, Andreas H. Ludewig, Irma R. Fernandez, Tyler R. Bales, Robert S. Weiss & Frank C. Schroeder

Journal: Nature Chemical Biology

PubMed ID: 38167917

Doi: 10.1038/s41589-023-01511-2

Products & Services: Antibody Modification and Purification Services

Omicron Spike confers enhanced infectivity and interferon resistance to SARS-CoV-2 in human nasal tissue

Authors: Guoli Shi , Tiansheng Li , Kin Kui Lai , Reed F Johnson , Jonathan W Yewdell , Alex A Compton