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SHU 9119

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The efficacy and specificity of SHU-9119 as an MC3/MC4 receptor antagonist in the rat was first validated in vitro and in vivo. In vitro, in heterologous cells expressing either rat MC3-R or MC4-R, the major MCR subtypes expressed in brain, SHU-9119 showed no intrinsic agonism.
RP13311
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Note

Antagonist of rat MC3 and mouse MC4 receptors.

产品概述
Sequence
Ac-Nle-cyclo[Asp-His-D-Nal(2')-Arg-Trp-Lys]-NH2
Molecular Formula C54H71N15O9
C Terminal Amidation
N Terminal Acetylation
Disulfide Bridge Asp2-Lys7
Molecular Weight 1074.23

产品属性
Purity > 95%
Solubility Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
Storage Storage at -20°C. Keep tightly closed.

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