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[Nle4, D-Phe7]-α-Melanocyte Stimulating Hormone (MSH), amide

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[Nle4, DPhe7]-alpha-MSH (NDP-MSH), a highly potent analogue of alpha-melanocyte-stimulating hormone (alpha-MSH), possesses nanomolar efficacies at all the melanocortin receptor subtypes except the MC2R. Evaluation of the melanocortin 'message' sequence of [Nle4, DPhe7]-alpha-MSH was performed on the human melanocortin receptor subtypes designated hMC1, hMC3R, hMC4R, and hMC5R.
RP10658CN
产品概述
Synonyms αMSH; a-MSH; aMSH; alpha-MSH; alphaMSH;α-Melanocyte Stimulating Hormone; αMelanocyte Stimulating Hormone; a-Melanocyte Stimulating Hormone; aMelanocyte Stimulating Hormone; alpha-Melanocyte Stimulating Hormone; alphaMelanocyte Stimulating Hormone; NDP-MSH[Nle4, D-Phe7]-α-MSH, amide
Description [Nle4, DPhe7]-alpha-MSH (NDP-MSH), a highly potent analogue of alpha-melanocyte-stimulating hormone (alpha-MSH), possesses nanomolar efficacies at all the melanocortin receptor subtypes except the MC2R. Evaluation of the melanocortin 'message' sequence of [Nle4, DPhe7]-alpha-MSH was performed on the human melanocortin receptor subtypes designated hMC1, hMC3R, hMC4R, and hMC5R.
Cas No 75921-69-6
Sequence
Ac-{SER}{TYR}{SER}{NLE}{GLU}{HIS}{d-PHE}{ARG}{TRP}{GLY}{LYS}{PRO}{VAL}-NH2
Sequence Shortening Ac-SYSNleEHfRWGKPV-NH2
Molecular Formula C78H111N21O19
C Terminal NH2
N Terminal Ac
Molecular Weight 1647.0
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产品属性
Purity > 95%
Form Lyophilized
Storage Store at -20°C. Keep tightly closed. Store in a cool dry place.
Note [Nle4,DPhe7] alpha-MSH is a hormone that stimulates melanogenesis and facilitates learning and memory. [Nle4,DPhe7] alpha-MSH can affect inflammatory and immune responses and peripheral nerve regeneration.
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