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Mezigdomide is effective alone and in combination with Menin inhibition in pre-clinical models of KMT2A-r and NPM1c AML
Authors: Wallace Bourgeois, Jevon A Cutler, Brandon J Aubrey, Daniela Wenge, Florian Perner, Cynthia Martucci, Jill A Henrich, Kelly Klega, Radoslaw P Nowak, Katherine Aleisha Donovan, Meaghan Boileau, Yanhe Wen, Charles Hatton, Athina A Apazidis, Sarah N Olsen, Nadia Kirmani, Yana Pikman, Jessica A Pollard, Jennifer A Perry, Adam S Sperling, Benjamin L Ebert, Gerard M McGeehan, Brian D Crompton, Eric S Fischer, Scott A Armstrong
Journal: Blood
PubMed ID: 38096371
Doi: 10.1182/blood.2023021105
Products & Services: Peptide Synthesis   
Immunoswitch Nanomodulators Enable Active Targeting and Selective Proliferation of Regulatory T Cells for Multiple Sclerosis Therapy
Authors: Xiaoshuang Wang , Zhilin Liu , Di Wang , Yingyu Zhang , Honglei Zhang , Fuxin Xue , Xianhong Wang , Zhaohui Tang , Xuemei Han
Journal: ACS Nano .
PubMed ID: 38113242
Doi: 10.1021/acsnano.3c09225
Products & Services: Catalog Peptides   
Publisher Correction: CD3ζ ITAMs enable ligand discrimination and antagonism by inhibiting TCR signaling in response to low-affinity peptides
Authors: Guillaume Gaud, Sooraj Achar, François X P Bourassa, John Davies, Teri Hatzihristidis, Seeyoung Choi, Taisuke Kondo, Selamawit Gossa, Jan Lee, Paul Juneau, Naomi Taylor, Christian S Hinrichs, Dorian B McGavern, Paul François, Grégoire Altan-Bonnet, Paul E Love
Journal: Nat Immunol
PubMed ID: 38057618
Doi: 10.1038/s41590-023-01725-5
Products & Services: Peptide Synthesis   
Elucidation of the structural basis for ligand binding and translocation in conserved insect odorant receptor co-receptors
Authors: Jody Pacalon, Guillaume Audic, Justine Magnat, Manon Philip, Jérôme Golebiowski, Christophe J Moreau, Jérémie Topin
Journal: Nat Commun
PubMed ID: 38081900
Doi: 10.1038/s41467-023-44058-5
Products & Services: Peptide Synthesis   
A new vaccination regimen using adenovirus-vectored vaccine confers effective protection against African swine fever virus in swine
Authors: Wenming Liu , Hengchun Li , Bo Liu , Tianxing Lv , Chenchen Yang , Si Chen , Liqiang Feng , Liangxue Lai , Ziyuan Duan , Xinwen Chen , Pingchao Li , Suhua Guan , Ling Chen
Journal: Emerg Microbes Infect .
PubMed ID: 37401832
Doi: 10.1080/22221751.2023.2233643
Products & Services: Peptide Synthesis   
A new gene family (BAPs) of bracovirus induces apoptosis of host hemocytes
Authors: Ze-Hua Wang, Xi-Qian Ye, Xiao-Tong Wu, Zhi-Zhi Wang, Jian-Hua Huang, Xue-Xin Chen
Journal: Virulence
PubMed ID: 36694288
Doi: 10.1080/21505594.2023.2171691
Products & Services: Peptide Synthesis   
Influence of a D-enantiomeric peptide on the anticorrosion ability of titanium with different surface roughness against Streptococcus mutans biofilms
Authors: Dan Wang, Jian Yu, He Liu, Tian Zhang, Evan F Haney, Robert E W Hancock, Lin Peng, Ya Shen
Journal: J Dent
PubMed ID: 37944630
Doi: 10.1016/j.jdent.2023.104777
Products & Services: Peptide Synthesis   
Rational design of a JAK1-selective siRNA inhibitor for the modulation of autoimmunity in the skin
Authors: Qi Tang, Hassan H Fakih, Mohammad Zain Ui Abideen, Samuel R Hildebrand, Khashayar Afshari, Katherine Y Gross, Jacquelyn Sousa, Allison S Maebius, Christina Bartholdy, Pia Pernille Søgaard, Malene Jackerott, Vignesh Hariharan, Ashley Summers, Xueli Fan, Ken Okamura, Kathryn R Monopoli, David A Cooper, Dimas Echeverria, Brianna Bramato, Nicholas McHugh, Raymond C Furgal, Karen Dresser, Sarah J Winter, Annabelle Biscans, Jane Chuprin, Nazgol-Sadat Haddadi, Shany Sherman, Ümmügülsüm Yıldız-Altay, Mehdi Rashighi, Jillian M Richmond, Claire Bouix-Peter, Carine Blanchard, Adam Clauss, Julia F Alterman, Anastasia Khvorova, John E Harris
Journal: Nat Commun
PubMed ID: 37925520
Doi: 10.1038/s41467-023-42714-4
Products & Services: Peptide Synthesis   
Structure and functional divergence of PIP peptide family revealed by functional studies on PIP1 and PIP2 in
Authors: Xiao-Song Yu, Hong-Run Wang, Fei-Fan Lei, Rui-Qi Li, Hui-Peng Yao, Jin-Bo Shen, Noor-Ul Ain, Yi Cai
Journal: Front Plant Sci
PubMed ID: 38078092
Doi: 10.3389/fpls.2023.1208549
Products & Services: Peptide Synthesis   
Rational immunosilencing of a promiscuous T-cell epitope in the capsid of an adeno-associated virus
Authors: So Jin Bing, Morten Seirup, Trish T Hoang, Susana S Najera, Collin Britten, Stephanee L Warrington, Shiang-Ling Chu, Ronit Mazor
Journal: Nat Biomed Eng
PubMed ID: 37996615
Doi: 10.1038/s41551-023-01129-8
Products & Services: Peptide Synthesis   
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