SARS-CoV-2 Spike protein (S1, E484K, K417T, N501Y, His Tag)

该产品已下架。

SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. Lineage P.1, also known as the Brazil(ian) variant is one of the variants of SARS-CoV-2. This variant has 17 amino acid changes, ten of which are in its spike protein, including these three designated to be of particular concern: N501Y, E484K and K417T. SARS-CoV-2 Spike protein (S1, E484K, K417T, N501Y, His Tag) carries a polyhistidine tag at the C-terminus.

产品编号	Z03602
规格	定制报价

联系我们

产品简介

Species

SARS-CoV-2

Protein Construction

Expressed with the mutations of E484K, K417T, N501Y.

S1 protein (Gln14-Arg685) Accession # P0DTC2	Poly-His
N-term	C-term

Purity

> 95% as analyzed by SDS-PAGE

Endotoxin Level

< 0.2 EU/μg of protein by gel clotting method

Biological Activity

This protein is validated to bind with human ACE2 in functional ELISA assay.

Expression System

CHO

Theoretical Molecular Weight

75.7 kDa

Formulation

Supplied as a solution in PBS, pH 7.4.

Concentration

Please refer to the COA for the specific lot.

Storage & Stability

Upon receiving, this product remains stable for up to 6 months at -20°C or below. Please avoid repeated freeze-thaw cycles.

技术背景

Target Background	SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. Lineage P.1, also known as the Brazil(ian) variant is one of the variants of SARS-CoV-2. This variant has 17 amino acid changes, ten of which are in its spike protein, including these three designated to be of particular concern: N501Y, E484K and K417T. SARS-CoV-2 Spike protein (S1, E484K, K417T, N501Y, His Tag) carries a polyhistidine tag at the C-terminus.
Synonyms	Lineage P.1; 20J/501Y.V3; VOC-202101/02; Brazil(ian) variant; Gamma variant
References	1. Variants: distribution of cases data. GOV.UK. Retrieved 27 February 2021. 2. COVID-19: Virologist says Brazilian coronavirus variant detected in UK is not the one 'of concern'. 3. Genomic characterisation of an emergent SARS-CoV-2 lineage in Manaus: preliminary findings.