SARS-CoV-2 Spike protein (RBD, E484K, K417T, N501Y, Avi & His Tag)-HRP

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SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. Lineage P.1, also known as the Brazil(ian) variant is one of the variants of SARS-CoV-2. This variant has 17 amino acid changes, ten of which are in its spike protein, including these three designated to be of particular concern: N501Y, E484K and K417T.

产品编号	Z03601
规格	定制报价

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产品简介

Species

SARS-CoV-2

Protein Construction

Expressed with the mutations of E484K, K417T, N501Y.

Spike RBD (Arg319-Ser591) Accession # P0DTC2	Avi	Poly-His
N-term		C-term

Conjugate

HRP

Biological Activity

This protein is validated to bind with human ACE2 (Cat. No. Z03516) in functional ELISA assay.

Expression System

CHO

Application

The optimal dilution ratio should be determined by the end user for specific applications.
ELISA 1:1000

Formulation

Supplied as a solution in PBS, pH 7.4, 0.1% ProClin 300.

Storage & Stability

Upon receiving, this product remains stable for up to 3 months at 2-8°C. Protect from light.

技术背景

Target Background	SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. Lineage P.1, also known as the Brazil(ian) variant is one of the variants of SARS-CoV-2. This variant has 17 amino acid changes, ten of which are in its spike protein, including these three designated to be of particular concern: N501Y, E484K and K417T.
Synonyms	Lineage P.1; 20J/501Y.V3; VOC-202101/02; Brazil(ian) variant; Gamma variant
References	1. Variants: distribution of cases data. GOV.UK. Retrieved 27 February 2021. 2. COVID-19: Virologist says Brazilian coronavirus variant detected in UK is not the one 'of concern'. 3. Genomic characterisation of an emergent SARS-CoV-2 lineage in Manaus: preliminary findings.