目录产品 » SARS-CoV-2 Spike protein (S1, His Tag)
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SARS-CoV-2 Spike protein (S1, His Tag)

SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. SARS-CoV-2 Spike Protein is composed of S1 domain and S2 domain. S1 contains a receptor-binding domain (RBD) that can specifically bind to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells. S protein plays an important role in the induction of neutralizing antibodies and T-cell responses, as well as protective immunity.
￥3800
Z03485-100

产品简介
Species SARS-CoV-2
Protein Construction
S1 protein (Val16-Arg685)
Accession # P0DTC2		 Poly-His
N-term C-term
Purity > 90% as analyzed by SDS-PAGE
Endotoxin Level < 0.2 EU/μg of protein by gel clotting method
Biological Activity SARS-CoV-2 Spike protein (S1) can bind with Human ACE2 in functional ELISA assay.
Expression System 293 Cells
Theoretical Molecular Weight 79 kDa
Formulation Supplied as a solution in PBS pH 7.2 containing 10% glycerol.
Concentration Please refer to the COA for the specific lot.
Storage & Stability Upon receiving, this product remains stable for 6 months at -20°C or below. Avoid repeated freeze-thaw cycles.
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SARS-CoV-2 Spike Protein (S1, His Tag)

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SARS-CoV-2 Spike Protein (S1, His Tag)

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SARS-CoV-2 Spike Protein (S1, His Tag)

Immobilized SARS-CoV-2 S1 protein(His Tag) (Cat. No. Z03485) at 1 μg/mL can bind ACE-2 Fc Chimera, Human (Cat. No. Z03516) with a serial dilution.
Mouse Anti-Human IgG Fc Antibody[HRP], mAb (Cat.No. A01854) is used as a secondary antibody (0.1 μg/mL). »

SARS-CoV-2 Spike Protein (S1, His Tag)

Lane 1: 1μg of SARS-CoV-2 Spike protein (S1, His Tag), reducing(R)
> 95% as analyzed by SDS-PAGE »

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技术背景
Target Background SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. SARS-CoV-2 Spike Protein is composed of S1 domain and S2 domain. S1 contains a receptor-binding domain (RBD) that can specifically bind to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells. S protein plays an important role in the induction of neutralizing antibodies and T-cell responses, as well as protective immunity.
Synonyms SARS-CoV-2 S1 protein; 2019-nCoV S1 protein
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For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.


相关文献
Kathrin Schanda, et al. Is there an immunological cross-reactivity of antibodies to the myelin oligodendrocyte glycoprotein and coronaviruses?. Brain Commun. (2024-03)
Andrei Komarov, et al. Dual-Antigen System Allows Elimination of False Positive Results in COVID-19 Serological Testing. Diagnostics (Basel). (2021-01)
Moutal A, et al. SARS-CoV-2 spike protein co-opts VEGF-A/neuropilin-1 receptor signaling to induce analgesia. Pain. (2021-01)