ACE-2, hFc, Human

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Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family. The ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase. ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency.

产品编号	Z03484
规格	定制报价

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产品简介

Species

Human

Protein Construction

ACE-2 (Gln18-Ser740) Accession # Q9BYF1	hFc
N-term	C-term

Purity

> 95% as analyzed by SDS-PAGE

Endotoxin Level

< 1 EU/μg of protein by LAL method

Biological Activity

ACE-2, hFc, Human can bind with S-RBD in functional ELISA assay.

Expression System

Human Cells

Theoretical Molecular Weight

110.5 kDa

Formulation

Supplied as a solution in 20 mM Tris-HCl, 300 mM NaCl, 1 mM ZnCl2, 10% Glycerol, pH 7.4.

Concentration

Please refer to the COA for the specific lot.

Storage & Stability

Upon receiving, this product remains stable for up to 6 months at -20°C or below. Avoid repeated freeze-thaw cycles.

技术背景

Target Background

Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family. The ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase. ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE 2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. It has high binding affinity to S-RBD.

Synonyms

Human Angiotensin-Converting Enzyme 2; ACE-2

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.