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目录产品 » 重组蛋白 » 细胞因子 » TRAIL Receptor-2, Human

TRAIL R-2, Human

Synonyms soluble TRAIL Receptor-2, DR5, TNFRSF10B, KILER, TRICK2A, TRICKB
Description TRAIL Receptor-2 is a cell-surface receptor involved in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced cell-death signaling. The death ligand TRAIL bears high potential as a new anticancer agent, as binding to the death receptors TRAIL-R1 or TRAIL-R2 triggers apoptosis in most cancer cells. TRAIL-R2 is associated with a decrease in the survival rates of breast cancer patients.
Accession No Q6FH58
Species Human
Source HEK 293
Biological Activity ED50 < 6 ng/ml, measured in a cell proliferation assay using RPMI-8226 cells in the presence of 25 ng/ml of human TRAIL.
Sequence
ALITQQDLAP QQRAAPQQKR SSPSEGLCPP GHHISEDGRD
CISCKYGQDY STHWNDLLFC LRCTRCDSGE VELSPCTTTR
NTVCQCEEGT FREEDSPEMC RKCRTGCPRG MVKVGDCTPW
SDIECVHKE

Measured Molecular Weight ~15 kDa, observed by reducing SDS-PAGE.
Purity > 95% as analyzed by SDS-PAGE and HPLC.
Formulation Lyophilized after extensive dialysis against PBS.
Reconstitution Reconstituted in ddH2O or PBS at 100 μg/ml.
Endotoxin Level < 0.2 EU/μg, determined by LAL method.
Storage Lyophilized recombinant Human TRAIL Receptor-2 remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, Human TRAIL Receptor-2 should be stable up to 1 week at 4°C or up to 2 months at -20°C.




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产品编号: Z03095
规格
价格
Z03095-10 10 ug ¥300.00
Z03095-50 50 ug ¥600.00
Z03095-1 1 mg ¥4500.00