目录产品 » 重组蛋白 » 细胞因子 » IL-25, Mouse

IL-25, Mouse

该产品已下架。
Interleukin-25 (IL-25), also known as interleukin-17E (IL-17E), is a cytokine that belongs to the IL-17 cytokine family together with IL-17A (named also IL-17), IL-17B, IL-17C, IL-17D and IL-17F. IL-25 has a heterodimeric receptor. The receptor is composed of two subunits IL-17RA and IL-17RB, it does not bind directly to IL-17RA, but this subunit is necessary for its functions, as well as IL-17RB which directly bind IL-25. IL-25 can induce NF-κB activation, and stimulate the production of IL-8 (named also CXCL8), which is the major chemotactic substance of neutrophils. Another important function of IL-25 is to support the Th2 immune response. IL-25 has been shown to induce the production of IL-4, IL-5 and IL-13. Evidence is the expression of IL-17RB on Th2 cells, not on Th1 and Th17. In addition, IL-25 is responsible for the decrease in IFN gamma.
Z02771
联系我们
Species Mouse
Protein Construction

Expressed with an N-terminal Met.

IL-25 (Val25-Leu166)
Accession # Q9CPT4
Purity > 95% as analyzed by SDS-PAGE
> 95% as analyzed by HPLC
Endotoxin Level < 1 EU/μg of protein by LAL method
Expression System E. coli
Theoretical Molecular Weight 15.8 kDa
Formulation Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4.
Reconstitution It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml.
Storage & Stability Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles.

Target Background Interleukin-25 (IL-25), also known as interleukin-17E (IL-17E), is a cytokine that belongs to the IL-17 cytokine family together with IL-17A (named also IL-17), IL-17B, IL-17C, IL-17D and IL-17F. IL-25 has a heterodimeric receptor. The receptor is composed of two subunits IL-17RA and IL-17RB, it does not bind directly to IL-17RA, but this subunit is necessary for its functions, as well as IL-17RB which directly bind IL-25. IL-25 can induce NF-κB activation, and stimulate the production of IL-8 (named also CXCL8), which is the major chemotactic substance of neutrophils. Another important function of IL-25 is to support the Th2 immune response. IL-25 has been shown to induce the production of IL-4, IL-5 and IL-13. Evidence is the expression of IL-17RB on Th2 cells, not on Th1 and Th17. In addition, IL-25 is responsible for the decrease in IFN gamma.
Synonyms IL25; IL17E; IL-25; interleukin 25

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.


喜欢新升级的网站吗?

讨厌

不喜欢

一般

喜欢

非常喜欢

*