Mycobacterium tuberculosis Protein Ag85A
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This is a T cell immunodominant CD8 peptide of the Ag85A mycobacterium tuberculosis protein, MHC class I H-2Ld-restricted epitope. Parenterally administered Mycobacterium bovis BCG vaccine confers only limited immune protection from pulmonary tuberculosis, and intranasal administration of vector-expressing AdAg85A represents an effective means of boosting immune protection by parenteral BCG vaccination.
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