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Corticotropin Releasing Factor, ovine

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Corticotropin Releasing Factor (CRF) is a hypothalamic peptide that releases ACTH and endorphin from the anterior pituitary. Corticotropin Releasing Factor is also a neurotransitter in the central nervous system, and is involved in autonomic and endocrine responses to stress.
RP10983
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Synonyms

CRFCorticotropin-releasing hormone (CRH)

Note

Corticotropin Releasing Factor (CRF) analog used to prepare iodinated CRF for receptor studies and immunoassay.

Cas No 9015-71-8
Sequence
{SER}{GLN}{GLU}{PRO}{PRO}{ILE}{SER}{LEU}{ASP}{LEU}{THR}{PHE}{HIS}{LEU}{LEU}{ARG}{GLU}{VAL}{LEU}{GLU}{MET}{THR}{LYS}{ALA}{ASP}{GLN}{LEU}{ALA}{GLN}{GLN}{ALA}{HIS}{SER}{ASN}{ARG}{LYS}{LEU}{LEU}{ASP}{ILE}{ALA}-NH2
Sequence Shortening SQEPPISLDLTFHLLREVLEMTKADQLAQQAHSNRKLLDIA-NH2
Molecular Formula C205H339N59O63S1
C Terminal NH2
Molecular Weight 4670.31

Purity > 95%
Solubility Insoluble in water. Dissolve peptide in 60% Acetonitrile with 0.1% TFA solution followed by water or desired buffer.
Storage Store at -20°C. Keep tightly closed. Store with desiccant.

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