Phosphotyrosine Antibody (18E10), mAb, Mouse

该产品已下架。

Phosphotyrosine is a tyrosine residue covalently bound to a phosphate via its hydroxyl group. A tyrosine kinase catalyzes the transfer of a phosphate from ATP to a tyrosine residue on the protein substrate. Tyrosine phosphorylation plays a key role in intracellular and cancer development. Many tyrosine kinases are l drug targets for different forms of cancer. Phosphotyrosine antibody specifically binds tophosphotyrosine residues. It is a valuablel tool to analyze tyrosine phosphorylation and monitor the activity of tyrosine kinase in high throughput drug discovery. GenScript Phosphotyrosine Antibody (18E10), mAb, Mouse is produced from a hybridoma resulting from the fusion of SP2/0-Ag14 myeloma and B-lymphocytes harvested from mouse immunized with phosphotyrosine containing carrier protein.

产品编号	A01818
规格	定制报价

联系我们

产品概述

Specificity	The antibody is specific for proteins containing phosphotyrosine residues. It does not cross-react with phosphoserine, phosphothreonine or nonphosphorylated tyrosine residues.
Host Species	Mouse
Immunogen	Phosphotyrosine containing carrier protein

产品属性

Concentration	0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide.
Reconstitution	Reconstitute the lyophilized product with deionized water (or equivalent) to a final concentration of 0.5 mg/ml.
Purification	Protein A affinity column
Clone ID	18E10D2

技术背景

Target Background

Phosphotyrosine is a tyrosine residue covalently bound to a phosphate via its hydroxyl group. A tyrosine kinase catalyzes the transfer of a phosphate from ATP to a tyrosine residue on the protein substrate. Tyrosine phosphorylation plays a key role in intracellular and cancer development. Many tyrosine kinases are l drug targets for different forms of cancer. Phosphotyrosine antibody specifically binds tophosphotyrosine residues. It is a valuablel tool to analyze tyrosine phosphorylation and monitor the activity of tyrosine kinase in high throughput drug discovery.
GenScript Phosphotyrosine Antibody (18E10), mAb, Mouse is produced from a hybridoma resulting from the fusion of SP2/0-Ag14 myeloma and B-lymphocytes harvested from mouse immunized with phosphotyrosine conjugated to KLH.

Synonyms

Mouse monoclonal to Phosphotyrosine/pY