目录产品 » MonoMethyl-Histone H2B type 2E (R79) Antibody, mAb, Rabbit
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MonoMethyl-Histone H2B type 2E (R79) Antibody, mAb, Rabbit

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
￥1200
A02867-50

产品概述
Specificity This product is specific to MonoMethyl-Histone H2B type 2E (R79)
Host Species Rabbit
Immunogen A synthesized peptide derived from human Histone H2B type 2E around the methylation site of R80
Species Reactivity Human; Mouse
Conjugate Unconjugated
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应用指导
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
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产品属性
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal
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图例
MonoMethyl-Histone H2B Type 2E (R79) Antibody, MAb, Rabbit

Western blot analysis of Histone H2B (mono methyl R79) expression in HeLa cell lysate. »

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技术背景
Target Background Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Synonyms H2B; H2BQ; GL105; H2B.1; H2BFQ; H2BGL105; H2R79me1;
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.