Specificity |
The product is specific for Dupilumab. |
Host Species |
Rabbit |
Immunogen |
Dupilumab |
Conjugate |
Unconjugated |
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product. |
Application |
Recommended Usage |
ELISA |
0.05-1 µg/ml |
|
Form |
Lyophilized |
Storage Buffer |
Lyophilized with PBS, pH 7.4, containing 0.02% sodium azide. |
Reconstitution |
Reconstitute the lyophilized powder with deionized water (or equivalent) to a final concentration of 0.5 mg/ml. |
Storage Instructions |
The lyophilized product remains stable up to 1 year at -20 °C from date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below. Avoid repeated freezing and thawing cycles. |
Purification |
Antigen affinity purification |
Isotype |
Rabbit IgG |
Clonality |
Polyclonal |
Note |
GenScript can customize this product per customer's request including product size, buffer components, etc. |
Target Background |
Dupilumab with trade name Dupixent, is an FDA-approved drug for the trea™ent of patients aged 6 years and older with moderate-to-severe atopic dermatitis. It is a human monoclonal antibody. Dupilumab binds to the interleukin-4 receptor alpha (IL-4Rα) subunit shared by the interleukin (IL)-4 and IL-13 receptor complexes, thereby inhibiting IL-4 and IL-13 signaling.GenScript Anti-Dupilumab Antibody, pAb, Rabbit is produced from sera of a rabbit immunized with Dupilumab. |
Synonyms |
Rabbit polyclonal to Dupixent |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.