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Human KRT20 Antibody (5G4), mAb, Mouse

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Keratin-20 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. KRT20 plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, it plays a role in the secretion of mucin in the small intestine. Diseases associated with KRT20 include Merkel cell carcinoma and ovarian Brenner tumor. Among its related pathways are cytoskeletal signaling and developmental biology.
A01893
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Specificity The product is specific for human KRT20. This antibody binds with recombinant KRT20 protein in ELISA and western blot.
Host Species Mouse
Immunogen Recombinant Human KRT20

Concentration 0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide. (It may be customized for bulk orders.)
Reconstitution Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/ml.
Purification Protein A affinity column
Clone ID 5G4

Target Background Keratin-20 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. KRT20 plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, it plays a role in the secretion of mucin in the small intestine. Diseases associated with KRT20 include Merkel cell carcinoma and ovarian Brenner tumor. Among its related pathways are cytoskeletal signaling and developmental biology.
Synonyms Mouse monoclonal to CK-20, CK20, cytokeratin 20, Cytokeratin-20, K20, keratin, keratin 20, type I, Keratin, type I cytoskeletal 20, Keratin-20, KRT21, Protein IT, type I cytoskeletal 20

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