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IP-10 Antibody (1H7D6), mAb, Mouse

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Interferon-gamma-inducible 10 kD protein (IP10)is a CXC chemokine with chemoattractant properties for CD4-positive T cells and inhibits early normal and leukemic hemopoietic progenitor proliferation. IP10 is produced by a wide variety of cell types ranging from neutrophils and monocytes to hepatocytes, endothelial cells, and keratinocytes. The cytokine is reported to be involved in a scala of inflammatory pathologies such as HIV encephalitis, cutaneous T cell lymphoma, chronic hepatitis and acute anterior uveitis. Various observations strongly suggest a role for the CXC chemokines IL-8 and IP10 to regulate angiogenic activity in cancer and in idiopathic pulmonary fibrosis. GenScript IP10 Antibody, mAb, Mouse is produced from the hybridoma resulting from fusion of Sp2/0 myeloma and lymphocytes obtained from mouse immunized with purified recombinant human protein IP10 (Swiss-Prot P02778).
A01563
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Specificity GenScript IP10 Antibody, mAb, Mouse detects human IP10
Host Species Mouse
Immunogen Purified recombinant human protein IP10 (Swiss-Prot: P02778)
Species Reactivity Human. This product has not been test with other species yet.

Concentration 0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide
Reconstitution Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.
Purification Protein A affinity column
Clone ID 1H7D6

Target Background Interferon-gamma-inducible 10 kD protein (IP10)is a CXC chemokine with chemoattractant properties for CD4-positive T cells and inhibits early normal and leukemic hemopoietic progenitor proliferation. IP10 is produced by a wide variety of cell types ranging from neutrophils and monocytes to hepatocytes, endothelial cells, and keratinocytes. The cytokine is reported to be involved in a scala of inflammatory pathologies such as HIV encephalitis, cutaneous T cell lymphoma, chronic hepatitis and acute anterior uveitis. Various observations strongly suggest a role for the CXC chemokines IL-8 and IP10 to regulate angiogenic activity in cancer and in idiopathic pulmonary fibrosis.
GenScript IP10 Antibody, mAb, Mouse is produced from the hybridoma resulting from fusion of Sp2/0 myeloma and lymphocytes obtained from mouse immunized with purified recombinant human protein IP10 (Swiss-Prot P02778).
Synonyms IP-10 Antibody, mAb, Mouse;

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