Human RANTES Antibody (2H8G2), mAb, Mouse

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RANTES is a chemoattractant for blood monocytes, memory T helper cells, and eosinophils. It causes the release of histamine from basophils and activates eosinophils and binds to CCR1, CCR3, CCR4, and CCR5. It is also one of the major HIV suppressive factors produced by CD8+ T cells. Recombinant RANTES protein induces a dose dependent inhibition of different strains of HIV 1, HIV 2, and simian immunodeficiency virus (SIV). Induced by mitogens, it is T cell and macrophage specific and belongs to the intercrine beta (chemokine CC) family. GenScript Human RANTES Antibody (2H8G2), mAb, Mouse is produced from the hybridoma resulting from fusion of Sp2/0 myeloma and lymphocytes obtained from mouse immunized with purified full length human recombinant RANTES protein (Swiss Prot: P13501).

产品编号	A01476
规格	定制报价

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产品概述

Specificity	GenScript Human RANTES Antibody (2H8G2), mAb, Mouse detects human RANTES protein.
Host Species	Mouse
Immunogen	purified full length human recombinant RANTES protein (Swiss Prot: P13501)
Species Reactivity	Human. Reactivity to other species has not been tested yet.

产品属性

Concentration	0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide
Reconstitution	Reconstitute the lyophilized powder with deionized water (or equivalent) to an final concentration of 0.5 mg/ml.
Purification	Protein A affinity column
Clone ID	2H8G2

技术背景

Target Background

RANTES is a chemoattractant for blood monocytes, memory T helper cells, and eosinophils. It causes the release of histamine from basophils and activates eosinophils and binds to CCR1, CCR3, CCR4, and CCR5. It is also one of the major HIV suppressive factors produced by CD8+ T cells. Recombinant RANTES protein induces a dose dependent inhibition of different strains of HIV 1, HIV 2, and simian immunodeficiency virus (SIV). Induced by mitogens, it is T cell and macrophage specific and belongs to the intercrine beta (chemokine CC) family.
GenScript Human RANTES Antibody (2H8G2), mAb, Mouse is produced from the hybridoma resulting from fusion of Sp2/0 myeloma and lymphocytes obtained from mouse immunized with purified full length human recombinant RANTES protein (Swiss Prot: P13501).

Synonyms

Mouse anti RANTES mAb; Mouse anti CCL5 mAb