PDI Antibody, pAb, Rabbit
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Protein Disulphide Isomerase (PDI) is a microsomal enzyme which locates in endoplasmic reticulum lumen. The enzyme catalyzes the formation and isomerization of intermolecular disulphide-bond that stabilizes three dimensional structure of many extracellular proteins. The upregulation of PDI represents an adaptive response to the accumulation of immature and denatured proteins which cause ER dysfunction in neurodegenerative disorders.GenScript Rabbit Anti-PDI Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide within residues 100-150 of human PDI (Swiss Prot: P07237).
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