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PDI Antibody, pAb, Rabbit

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Protein Disulphide Isomerase (PDI) is a microsomal enzyme which locates in endoplasmic reticulum lumen. The enzyme catalyzes the formation and isomerization of intermolecular disulphide-bond that stabilizes three dimensional structure of many extracellular proteins. The upregulation of PDI represents an adaptive response to the accumulation of immature and denatured proteins which cause ER dysfunction in neurodegenerative disorders.GenScript Rabbit Anti-PDI Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide within residues 100-150 of human PDI (Swiss Prot: P07237).
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Specificity GenScript Rabbit Anti-PDI Polyclonal Antibody detects endogenous levels of human, mouse, and rat PDI.
  • Positive Control:
  • K562, HepG2, A431, Hela, Ramos, mouse brain and rat brain lysates
    Host Species Rabbit
    Immunogen KLH-coupled synthetic peptide within residues 100-150 of human PDI (Swiss Prot: P07237).
    Species Reactivity Human, mouse, and rat. This product has not been tested with other species yet.

    Concentration 0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide.
    Reconstitution Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.
    Purification Immunoaffinity chromatography

    Target Background Protein Disulphide Isomerase (PDI) is a microsomal enzyme which locates in endoplasmic reticulum lumen. The enzyme catalyzes the formation and isomerization of intermolecular disulphide-bond that stabilizes three dimensional structure of many extracellular proteins. The upregulation of PDI represents an adaptive response to the accumulation of immature and denatured proteins which cause ER dysfunction in neurodegenerative disorders.
    GenScript Rabbit Anti-PDI Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide within residues 100-150 of human PDI (Swiss Prot: P07237).
    Synonyms PDI A1 antibody; ER Marker

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