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Nestin Antibody, pAb, Rabbit

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Nestin is a class IV intermediate filament protein which is abundantly expressed in neuroepithelial stem cells early in embryogenesis. It contains a short head domain and a long tail domain. Upon differentiation, nestin is down regulated and is replaced by other tissue specific intermediate filaments. It serves as a predominant marker for stem/progenitor cells, glioma cells, and tumor endothelial cells in the mammalian CNS.GenScript Rabbit Anti-Nestin Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide from within residues 1280-1330 of human Nestin (Swiss Prot: P48681).
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Specificity GenScript Rabbit Anti-Nestin Polyclonal Antibody detects endogenous levels of human Nestin. It is predicted to react with mouse and rat according to sequence homology.
Host Species Rabbit
Immunogen KLH-coupled synthetic peptide from within residues 1280-1330 of human Nestin (Swiss Prot: P48681).
Species Reactivity Human. This product has not been tested with other species yet.

Concentration 0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide
Reconstitution Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.
Purification Immunoaffinity chromatography

Target Background Nestin is a class IV intermediate filament protein which is abundantly expressed in neuroepithelial stem cells early in embryogenesis. It contains a short head domain and a long tail domain. Upon differentiation, nestin is down regulated and is replaced by other tissue specific intermediate filaments. It serves as a predominant marker for stem/progenitor cells, glioma cells, and tumor endothelial cells in the mammalian CNS.

GenScript Rabbit Anti-Nestin Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide from within residues 1280-1330 of human Nestin (Swiss Prot: P48681).
Synonyms Rabbit Anti-Nestin pAb;

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