CXCR2 Antibody, pAb, Rabbit
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CXCR2 is a member of the GPCR family (subfamily, chemokine). It is a receptor for Interleukin 8 (IL8), which is a powerful neutrophil chemotactic factor. Binding of IL8 with the receptor activates neutrophils. This response is mediated by a second messenger system in which G-protein activates phosphatidyl inositol-calcium. This receptor binds to IL8, GRO/MGSA, and NAP2 with a high affinity. Its expression has been reported to be in a wide variety of tissues.GenScript Rabbit Anti-CXCR2 Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide derived from N-terminal extracellular domain of human CXCR2.
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