EB1 Antibody, pAb, Rabbit
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EB1, also known as MAPRE1, is a regulator of microtubule dynamics that localizes at the growing plus ends of microtubules and the centrosome. It is important for anchoring cytoplasmic microtubule (MT) minus ends to the subdistal appendages of the mother centriole. EB1 plays a role in the regulation of MT dynamics and is implicated in regulation of cell polarity and chromosome stability. EB1 proteins interact physically with the adenomatous polyposis coli (APC) tumor suppressor protein, targeting APC to microtubule plus ends.GenScript Rabbit Anti-EB1 Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide within residues 130-180 of human EB1 protein (Swiss Prot: Q15691).
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