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Single-molecule assay guided crRNA optimization enhances specific microRNA detection by CRISPR-Cas12a
Authors: Kaizhao Chen, Wenjun Sun, Mingtian Zhong, Jiaqi Xie, Yongkun Huo, Xiuqi Lu, Ziting Chen, Bo Sun, Xingxu Huang, Xinjie Wang, Ming Liu , Xiaodong Ma, Peixiang Ma
Journal: Sensors and Actuators B: Chemical
Doi: 10.1016/j.snb.2024.135389
Minimizing the ratio of ionizable lipid in lipid nanoparticles for in vivo base editing
Authors: Qiubing Chen, Xuebin Wang, Yizhou Zhang, Ming Tian, Junyi Duan, Ying Zhang, Hao Yin
Journal: NSR
Doi: 10.1093/nsr/nwae135
Products & Services: Gene Synthesis   
Phenotypic characterization of sorghum seedlings and expression patterns of SNAC1 and DREB1A genes under water‑stress: an insight towards developing resilient cultivars
Authors: David Adedayo Animasaun · Khadijat Adetoun Adedoyin · Afeez Taiwo Bakare · Kabir Adeniran Mustapha · Mary Anuoluwapo Akinbobola · Kafayat Folasade Awujoola · Jonathan Toyin Ogunjobi
Journal: springerlink
Doi: 10.1007/s10722-024-01956-x
Products & Services: Gene Synthesis   
Human IgG Fc-engineering for enhanced plasma half-life, mucosal distribution and killing of cancer cells and bacteria
Authors: Stian Foss , Siri A Sakya, Leire Aguinagalde, Marta Lustig, Jutamas Shaughnessy, Ana Rita Cruz , Lisette Scheepmaker, Line Mathiesen, Fulgencio Ruso-Julve, Aina Karen Anthi, Torleif Tollefsrud Gjølberg
Journal: Nature Communications
PubMed ID: 38453922
Doi: 10.1038/s41467-024-46321-9
Products & Services: Gene Synthesis   
Decoding chromatin states by proteomic profiling of nucleosome readers
Authors: Saulius Lukauskas, Andrey Tvardovskiy, Nhuong V Nguyen , Mara Stadler, Peter Faull, Tina Ravnsborg, Bihter Özdemir Aygenli, Scarlett Dornauer, Helen Flynn, Rik G H Lindeboom, Teresa K Barth, Kevin Brockers, Stefanie M Hauck, Michiel Vermeulen, Ambrosius P Snijders, Christian L Müller, Peter A DiMaggio, Ole N Jensen, Robert Schneider, Till Bartke
Journal: Nature
PubMed ID: 38448585
Doi: 10.1038/s41586-024-07141-5
Products & Services: Codon Optimization   
Filamentous fungus-produced human monoclonal antibody provides protection against SARS-CoV-2 in hamster and non-human primate models
Authors: Franziska K Kaiser, Mariana Gonzalez Hernandez, Nadine Krüger, Ellinor Englund, Wenjuan Du, Anna Z Mykytyn, Mathijs P Raadsen, Mart M Lamers
Journal: Nature Communications
PubMed ID: 38485931
Doi: 10.1038/s41467-024-46443-0
Products & Services: Codon Optimization   
Alternative low-populated conformations prompt phase transitions in polyalanine repeat expansions
Authors: Rosa Antón, Miguel Á Treviño, David Pantoja-Uceda, Sara Félix, María Babu, Eurico J Cabrita, Markus Zweckstetter, Philip Tinnefeld, Andrés M Vera, Javier Oroz
Journal: Nature
PubMed ID: 38431667
Doi: 10.1038/s41467-024-46236-5
Products & Services: Gene Synthesis   
An alphacoronavirus polymerase structure reveals conserved replication factor functions
Authors: Thomas K Anderson, Peter J Hoferle, Kennan J Chojnacki, Kenneth W Lee, Joshua J Coon, Robert N Kirchdoerfer
Journal: Nucleic Acids Research
PubMed ID: 38442273
Doi: 10.1093/nar/gkae153
Products & Services: Codon Optimization   
Determinants of CRISPR Cas12a nuclease activation by DNA and RNA targets 
Authors: Eric A Nalefski, Remy M Kooistra, Ishira Parikh, Samantha Hedley, Karunya Rajaraman, Damian Madan
Journal: Nucleic Acids Research
PubMed ID: 38477377
Doi: 10.1093/nar/gkae152
Products & Services: Gene Synthesis   
Biochemical and structural analysis of N-myristoyltransferase mediated protein tagging
Authors: Paul Monassa , Frédéric Rivière , Cyril Dian , Frédéric Frottin , Carmela Giglione , Thierry Meinnel
Journal: Methods Enzymol .
PubMed ID: 37230587
Doi: 10.1016/bs.mie.2023.02.016
Products & Services: Peptide Synthesis   
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