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Increasing β-hexosaminidase A activity using genetically modified mesenchymal stem cells
Authors: Alisa A Shaimardanova , Daria S Chulpanova , Valeriya V Solovyeva 1, Shaza S Issa , Aysilu I Mullagulova , Angelina A Titova , Yana O Mukhamedshina , Anna V Timofeeva , Alexander M Aimaletdinov , Islam R Nigmetzyanov , Albert A Rizvanov
Journal: Neural Regen Res .
PubMed ID: 37488869
Doi: 10.4103/1673-5374.375328
Products & Services: Gene Synthesis   
TREM2 variants that cause early dementia and increase Alzheimer's disease risk affect gene splicing
Authors: Kostantin Kiianitsa, Maria E Lukes, Brian J Hayes, Julianna Brutman, Paul N Valdmanis, Thomas D Bird, Wendy H Raskind, Olena Korvatska
Journal: Brain
PubMed ID: 38226698
Doi: 10.1093/brain/awae014
Products & Services: Gene Synthesis   Mutagenesis Services   Plasmid DNA Preparation   
Stabilization of the Metastable Pre-Fusion Conformation of the SARS-CoV-2 Spike Glycoprotein through N-Linked Glycosylation of the S2 Subunit
Authors: Fuwen Zan, Yao Zhou, Ting Chen , Yahan Chen, Zhixia Mu, Zhaohui Qian , Xiuyuan Ou
Journal: Viruses.
PubMed ID: 38399999
Doi: 10.3390/v16020223
Products & Services: Gene Synthesis   
Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy
Authors: Binh An Nguyen , Virender Singh , Shumaila Afrin , Anna Yakubovska , Lanie Wang , Yasmin Ahmed , Rose Pedretti , Maria Del Carmen Fernandez-Ramirez , Preeti Singh , Maja Pękała , Luis O Cabrera Hernandez , Siddharth Kumar , Andrew Lemoff , Roman Gonzalez-Prieto , Michael R Sawaya , David S Eisenberg , Merrill Douglas Benson , Lorena Saelices
Journal: Nat Commun
PubMed ID: 38233397
Doi: 10.1038/s41467-024-44820-3
Products & Services: Gene Synthesis   
Cryo-EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH
Authors: Niraj Kumar , Shivani Sharma , Prem S Kaushal
Journal: Nat Commun
PubMed ID: 38245551
Doi: 10.1038/s41467-024-44879-y
Products & Services: Gene Synthesis   
Cyclic di-GMP inhibits nitrate assimilation by impairing the antitermination function of NasT in Pseudomonas putida
Authors: Liang Nie, Yujie Xiao, Tiantian Zhou, Haoqi Feng, Meina He, Qingyuan Liang, Kexin Mu, Hailing Nie, Qiaoyun Huang, Wenli Chen
Journal: Nucleic Acids Res
PubMed ID: 38000372
Doi: 10.1093/nar/gkad1117
Products & Services: Gene Synthesis   
Glycosylase-based base editors for efficient T-to-G and C-to-G editing in mammalian cells
Authors: Lijun Ye , Dongdong Zhao , Ju Li , Yiran Wang , Bo Li , Yuanzhao Yang , Xueting Hou , Huibin Wang , Zhandong Wei , Xiaoqi Liu , Yaqiu Li, Siwei Li , Yajing Liu , Xueli Zhang , Changhao Bi
Journal: Nat Biotechnol .
PubMed ID: 38168994
Doi: 10.1038/s41587-023-02050-w
Products & Services: Gene Synthesis   Gene Synthesis   
Tomato-made edible COVID-19 vaccine TOMAVAC induces neutralizing IgGs in the blood sera of mice and humans
Authors: Zabardast T Buriev, Shukhrat E Shermatov, Dilshod E Usmanov, Mukhammadjon K Mirzakhmedov, Khurshida A Ubaydullaeva, Venera S Kamburova, Bakhtiyor K Rakhmanov, Mirzakamol S Ayubov, Adkham N Abdullaev
Journal: Front Nutr
PubMed ID: 38260078
Doi: 10.3389/fnut.2023.1275307
Products & Services: Gene Synthesis   
Streptococcus anginosus promotes gastric inflammation, atrophy, and tumorigenesis in mice
Authors: Kaili Fu 1, Alvin Ho Kwan Cheung 2, Chi Chun Wong 1, Weixin Liu 1, Yunfei Zhou 1, Feixue Wang 1, Pingmei Huang 1, Kai Yuan 1, Olabisi Oluwabukola Coker 1, Yasi Pan 1, Danyu Chen 1, Nga Man Lam 3, Mengxue Gao 4, Xiang Zhang 1, He Huang 4, Ka Fai To 2, Joseph Jao Yiu Sung 5, Jun Yu
Journal: Cell
PubMed ID: 38295787
Doi: 10.1016/j.cell.2024.01.004
Products & Services: Gene Synthesis   
Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes
Authors: Zebin Tong , Huasong Ai, Ziyu Xu , Kezhang He , Guo-Chao Chu, Qiang Shi , Zhiheng Deng, Qiaomei Xue , Maoshen Sun, Yunxiang Du , Lujun Liang, Jia-Bin Li , Man Pan , Lei Liu
Journal: Nat Struct Mol Biol .
PubMed ID: 38177667
Doi: 10.1038/s41594-023-01141-1
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