43Gap 26, Connexin Mimetic

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This Gap 26 peptide is derived from the first extracellular loop sequence of connexin (Cx) 43. This short mimetic peptide reversibly inhibits the gap junction-dependent propagation of Ca2+ waves between tracheal airway epithelial cells. Connexins, or gap junctions, are a family of structurally-related transmembrane proteins. Gap junctions contain channels that allow the passage of ions and small molecules between adjacent cells molecules. Calcium and inositol phosphates are among the second messengers that can pass through gap junction channels.

产品编号	RP20274
规格	定制报价

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产品概述

Description	This Gap 26 peptide is derived from the first extracellular loop sequence of connexin (Cx) 43. This short mimetic peptide reversibly inhibits the gap junction-dependent propagation of Ca2+ waves between tracheal airway epithelial cells. Connexins, or gap junctions, are a family of structurally-related transmembrane proteins. Gap junctions contain channels that allow the passage of ions and small molecules between adjacent cells molecules. Calcium and inositol phosphates are among the second messengers that can pass through gap junction channels.
Sequence	{Val}{Cys}{Tyr}{Asp}{Lys}{Ser}{Phe}{Pro}{Ile}{Ser}{His}{Val} {Arg}
Sequence Shortening	VCYDKSFPISHVR
Molecular Formula	C₇₀H₁₀₇N₁₉O₁₉S
Molecular Weight	1550.79