目录产品 » 稳定细胞系 » Human Recombinant CTLA4 Stable Cell Line
CHO-K1/CTLA4 Stable Cell Line

FACS analysis of CTLA4 expression in CHO-K1/CTLA4 cells.

CHO-K1/CTLA4 Stable Cell Line

CTLA4 or CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152 (cluster of differentiation 152), is a protein receptor that functions as an immune checkpoint and downregulates immune responses. CTLA4 is constitutively expressed in regulatory T cells but only upregulated in conventional T cells after activation – a phenomenon which is particularly notable in cancers. It acts as an "off" switch when bound to CD80 or CD86 on the surface of antigen-presenting cells. The CTLA-4 protein is encoded by the Ctla4 gene in mice and the CTLA4 gene in humans.
M00530
¥85000

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Description

CTLA4 or CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152 (cluster of differentiation 152), is a protein receptor that functions as an immune checkpoint and downregulates immune responses. CTLA4 is constitutively expressed in regulatory T cells but only upregulated in conventional T cells after activation – a phenomenon which is particularly notable in cancers. It acts as an "off" switch when bound to CD80 or CD86 on the surface of antigen-presenting cells.<br/>
The CTLA-4 protein is encoded by the Ctla4 gene in mice and the CTLA4 gene in humans.

Synonyms

ALPS5; CD; CD152; CELIAC3; GRD4; GSE; IDDM12

Applications Binding assay or use as immunogen.

Storage Liquid nitrogen immediately upon receiving
Species Human
Stability 15 passages

Freeze Medium 95% complete growth medium, 5% (V/V) DMSO (Cat. #D2650, Sigma)
Culture Medium F-12K (Kaighn’s), 10% FBS, 8 μg/ml Puromycin (Cat. #A11138-03, Gibco)

  • CHO-K1/CTLA4 Stable Cell Line
  • CHO-K1/CTLA4 Stable Cell Line

    FACS analysis of CTLA4 expression in CHO-K1/CTLA4 cells.


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