金斯瑞为客户提供种类丰富的GPCR和离子通道稳定细胞系。凭借密码子优化和载体设计的专利技术，我们成功克服了细胞表面功能蛋白表达水平低的难题。金斯瑞所有的细胞系均针对钙流检测或其他检测中的信背比(S/B ratio)进行了优化，并通过了16次传代的稳定性验证。另外，金斯瑞还提供稳定细胞系的构建服务，以满足您的特殊需求。
超家族 |
配体类型 |
受体家族 |
受体 |
细胞系名称 |
产品编号 |
A |
Non-peptide |
Acetylcholine (muscarinic) |
M1 / CHRM1 |
CHO-K1/M1 |
M00185 |
A |
Non-peptide |
Acetylcholine (muscarinic) |
M2 / CHRM2 |
CHO-K1/M2/Gα15 |
M00258 |
A |
Non-peptide |
Acetylcholine (muscarinic) |
M3 / CHRM3 |
CHO-K1/M3 |
M00259 |
A |
Non-peptide |
Acetylcholine (muscarinic) |
M4 / CHRM4 |
CHO-K1/M4/Gα15 |
M00238 |
A |
Non-peptide |
Acetylcholine (muscarinic) |
M5 / CHRM5 |
CHO-K1/M5 |
M00186 |
A |
Non-peptide |
Adenosine |
ADORA1 |
CHO-K1/ADORA1/Gα15 |
M00324 |
A |
Non-peptide |
Adenosine |
ADORA1 |
293/ADORA1/Gα15 |
M00255 |
A |
Non-peptide |
Adenosine |
ADORA2A |
CHO-K1/ADORA2A/Gα15 |
M00246 |
A |
Non-peptide |
Adenosine |
ADORA2B |
CHO-K1/ADORA2B/Gα15 |
M00329 |
A |
Non-peptide |
Adenosine |
ADORA3 |
CHO-K1/ADORA3/Gqi5 |
M00464 |
A |
Non-peptide |
Adrenoceptors |
ADRA1A |
CHO-K1/ADRA1A |
M00225 |
A |
Non-peptide |
Adrenoceptors |
ADRA1B |
CHO-K1/ADRA1B |
M00260 |
A |
Non-peptide |
Adrenoceptors |
ADRA1D |
CHO-K1/ADRA1D |
M00340 |
A |
Non-peptide |
Adrenoceptors |
ADRA2A |
CHO-K1/ADRA2A/Gα15 |
M00281 |
A |
Non-peptide |
Adrenoceptors |
ADRA2B |
CHO-K1/ADRA2B/Gqi5 |
M00454 |
A |
Non-peptide |
Adrenoceptors |
ADRA2C |
CHO-K1/ADRA2C/Gα15 |
M00252 |
A |
Non-peptide |
Adrenoceptors |
ADRB1 |
CHO-K1/ADRB1/Gα15 |
M00269 |
A |
Non-peptide |
Adrenoceptors |
ADRB2 |
CHO-K1/ADRB2/Gα15 |
M00308 |
A |
Non-peptide |
Adrenoceptors |
ADRB3 |
293/ADRB3/CRE-Luc |
M00335 |
A |
Peptide |
Anaphylotoxin |
C5a / C5AR1 |
CHO-K1/C5a/Gα15 |
M00327 |
A |
Peptide |
Angiotensin |
AT1 |
293T/AT1 |
M00448 |
A |
Peptide |
Angiotensin |
AT1 |
HEK293/AT1 |
M00458 |
A |
Peptide |
Apelin |
AGTRL1 |
CHO-K1/AGTRL1/Gα15 |
M00245 |
A |
Non-peptide |
Bile acid |
GPBAR1 |
CHO-K1/GPBAR1 |
M00432 |
A |
Peptide |
Bombesin |
BB1 / NMBR |
CHO-K1/BB1 |
M00254 |
A |
Peptide |
Bombesin |
BB2 / GRPR |
CHO-K1/BB2 |
M00182 |
A |
Peptide |
Bombesin |
BB3 / BRS3 |
CHO-K1/BB3 |
M00183 |
A |
Peptide |
Bradykinin |
B1 / BDKRB1 |
CHO-K1/B1/Gα15 |
M00482 |
A |
Peptide |
Bradykinin |
B2 / BDKRB2 |
CHO-K1/B2/Gα15 |
M00184 |
A |
Non-peptide |
Cannabinoid |
CB1 / CNR1 |
CHO-K1/CB1/Gα15 |
M00299 |
A |
Non-peptide |
Cannabinoid |
CB2 / CNR2 |
CHO-K1/CB2 |
M00433 |
A |
Peptide |
Chemoattractant |
ChemR23 / CMKLR1 |
CHO-K1/CMKLR1/Gα15 |
M00301 |
A |
Peptide |
Cholecystokinin |
CCKA |
CHO-K1/CCKA/Gα15 |
M00271 |
A |
Peptide |
Cholecystokinin |
CCKB |
CHO-K1/CCKB |
M00154 |
A |
Non-peptide |
Dopamine |
D1 / DRD1 |
CHO-K1/D1 |
M00247 |
A |
Non-peptide |
Dopamine |
D2 / DRD2 |
CHO-K1/D2/Gα15 |
M00152 |
A |
Non-peptide |
Dopamine |
D2S / DRD2S |
CHO-K1/D2S/Gα15 |
M00274 |
A |
Non-peptide |
Dopamine |
D4 / DRD4 |
293/D4 |
M00477 |
A |
Non-peptide |
Dopamine |
D5 / DRD5 |
CHO-K1/D5/Gα15 |
M00322 |
A |
Peptide |
Endothelin |
EDNRA |
CHO-K1/EDNRA |
M00149 |
A |
Peptide |
Endothelin |
EDNRB |
CHO-K1/EDNRB |
M00150 |
A |
Non-peptide |
Free Fatty Acid |
FFA1 / GPR40 |
CHO-K1/FFA1/Gα15 |
M00273 |
A |
Non-peptide |
Free Fatty Acid |
FFA2 / GPR43 |
CHO-K1/FFA2/Gα15 |
M00437 |
A |
Peptide |
Galanin |
GAL1 |
CHO-K1/GAL1/Gα15 |
M00277 |
A |
Peptide |
Galanin |
GAL2 |
CHO-K1/GAL2 |
M00209 |
A |
Peptide |
Ghrelin |
GHSR |
CHO-K1/GHSR |
M00189 |
A |
Peptide |
Gonadotropin-releasing Hormone |
GNRHR |
CHO-K1/GNRHR/Gα15 |
M00426 |
A |
Non-peptide |
Histamine |
H1 |
293/H1 |
M00131 |
A |
Non-peptide |
Histamine |
H2 |
CHO-K1/H2/Gα15 |
M00306 |
A |
Non-peptide |
Histamine |
H3 |
CHO-K1/H3/Gα15 |
M00331 |
A |
Non-peptide |
Histamine |
H4 |
CHO-K1/H4/Gα15 |
M00289 |
A |
Peptide |
KiSS1-derived Peptide |
KiSS1 / GPR54 |
CHO-K1/KiSS1 |
M00190 |
A |
Non-peptide |
Leukotriene |
CysLT1 |
CHO-K1/CysLT1/Gα15 |
M00462 |
A |
Non-peptide |
Leukotriene |
CysLT2 |
CHO-K1/CysLT2 |
M00449 |
A |
Non-peptide |
Leukotriene |
LTB4 |
CHO-K1/LTB4/Gα15 |
M00435 |
A |
Non-peptide |
Leukotriene |
OXE / OXER1 |
CHO-K1/OXE-Flag/Gα15 |
M00488 |
A |
Non-peptide |
Lysophospholipid |
EDG4 / LPA2 |
RH7777/EDG4 |
M00463 |
A |
Non-peptide |
Lysophospholipid |
EDG6 / S1P4 |
RH7777/EDG6 |
M00465 |
A |
Peptide |
Melanin-concentrating Hormone |
MCH1 |
293/MCH1 |
M00211 |
A |
Peptide |
Melanin-concentrating Hormone |
MCH2 |
CHO-K1/MCH2 |
M00280 |
A |
Peptide |
Melanocortin |
MC2 |
CHO-K1/MC2/Gα15 |
M00336 |
A |
Peptide |
Melanocortin |
MC3 |
CHO-K1/MC3/Gα15 |
M00242 |
A |
Peptide |
Melanocortin |
MC3 |
293/MC3/CRE-Luc |
M00337 |
A |
Peptide |
Melanocortin |
MC4 |
CHO-K1/MC4/Gα15 |
M00272 |
A |
Peptide |
Melanocortin |
MC5 |
CHO-K1/MC5/Gα15 |
M00243 |
A |
Peptide |
Melatonin |
MT1 / MTNR1A |
CHO-K1/MT1/Gα15 |
M00424 |
A |
Peptide |
Melatonin |
MT2 / MTNR1B |
CHO-K1/MT2/Gα15 |
M00312 |
A |
Peptide |
Motilin |
MTLR |
CHO-K1/MTLR/Gα15 |
M00347 |
A |
Peptide |
Neuromedin U |
NMU1 |
CHO-K1/NMU1 |
M00191 |
A |
Peptide |
Neuromedin U |
NMU2 |
293T/NMU2 |
M00244 |
A |
Peptide |
Neuropeptide B/W |
NPBW1 / GPR7 |
CHO-K1/NPBW1/Gα15 |
M00452 |
A |
Peptide |
Neuropeptide FF |
NPFF1 / GPR147 |
CHO-K1/NPFF1/Gα15 |
M00431 |
A |
Peptide |
Neuropeptide FF |
NPFF2 / GPR74 |
CHO-K1/NPFF2/Gα15 |
M00474 |
A |
Peptide |
Neuropeptide S |
NPS1a |
CHO-K1/NPS1a/Gα15 |
M00338 |
A |
Peptide |
Neuropeptide S |
NPS1b |
CHO-K1/NPS1b/Gα15 |
M00344 |
A |
Peptide |
Neuropeptide Y |
NPY1 |
CHO-K1/NPY1/Gα15 |
M00192 |
A |
Peptide |
Neuropeptide Y |
NPY1 |
293/NPY1 |
M00430 |
A |
Peptide |
Neuropeptide Y |
NPY2 |
CHO-K1/NPY2/Gqi5 |
M00460 |
A |
Peptide |
Neuropeptide Y |
NPY4 / PPYR1 |
CHO-K1/NPY4/Gα15 |
M00237 |
A |
Peptide |
Neurotensin |
NTS1 |
CHO-K1/NTS1 |
M00194 |
A |
Non-peptide |
Nicotinic Acid |
NIACR1 / GPR109A |
CHO-K1/NIACR1/Gα15 |
M00428 |
A |
Peptide |
N-Formyl Peptide |
FPR1 |
CHO-K1/FPR1/Gα15 |
M00429 |
A |
Peptide |
N-Formyl Peptide |
FPRL1 |
CHO-K1/FPRL1/Gα15 |
M00305 |
A |
Peptide |
Opioid |
OPRD1 |
CHO-K1/OPRD1/Gα15 |
M00323 |
A |
Peptide |
Opioid |
OPRK1 |
CHO-K1/OPRK1/Gα15 |
M00290 |
A |
Peptide |
Opioid |
OPRL1 |
CHO-K1/OPRL1/Gα15 |
M00447 |
A |
Peptide |
Opioid |
OPRM1 |
CHO-K1/OPRM1/Gα15 |
M00304 |
A |
Peptide |
Orexin |
OX1 |
CHO-K1/OX1 |
M00224 |
A |
Peptide |
Orexin |
OX2 |
CHO-K1/OX2 |
M00316 |
A |
Peptide |
Oxytocin |
OT / OXTR |
CHO-K1/OXTR |
M00195 |
A |
Peptide |
Peptide P518 |
GPR103 |
CHO-K1/GPR103/Gα15 |
M00321 |
A |
Non-peptide |
Platelet Activating Factor |
PAF / PTAFR |
CHO-K1/PTAFR |
M00262 |
A |
Peptide |
Prolactin Releasing Peptide |
PRLHR |
CHO-K1/PRLHR |
M00341 |
A |
Non-peptide |
Prostanoid |
DP1 / PTGDR |
CHO-K1/DP1/Gα15 |
M00453 |
A |
Non-peptide |
Prostanoid |
DP2 / GPR44 |
CHO-K1/DP2/Gα15 |
M00436 |
A |
Non-peptide |
Prostanoid |
FP / PTGFR |
293/FP/Gα15 |
M00155 |
A |
Non-peptide |
Prostanoid |
EP1 / PTGER1 |
293/EP1 |
M00228 |
A |
Non-peptide |
Prostanoid |
EP2 / PTGER2 |
CHO-K1/EP2/Gα15 |
M00311 |
A |
Non-peptide |
Prostanoid |
EP4 / PTGER4 |
293/EP4 |
M00485 |
A |
Non-peptide |
Prostanoid |
IP1 / PTGIR |
CHO-K1/IP1/Gα15 |
M00310 |
A |
Non-peptide |
Prostanoid |
TP / TBXA2R |
293/TP |
M00309 |
A |
Peptide |
Proteinase-activated Receptor |
PAR2 / F2RL1 |
CHO-K1/PAR2/Gα15 |
M00446 |
A |
Peptide |
Proteinase-activated Receptor |
PAR4 / F2RL3 |
CHO-K1/PAR4 |
M00206 |
A |
Non-peptide |
Proton-sensor |
GPR68 |
CHO-K1/GPR68/Gα15 |
M00439 |
A |
Non-peptide |
Purinergic |
P2Y1 |
1321N1/P2Y1 |
M00250 |
A |
Non-peptide |
Purinergic |
P2Y2 |
1321N1/P2Y2 |
M00318 |
A |
Non-peptide |
Purinergic |
P2Y4 |
1321N1/P2Y4 |
M00297 |
A |
Non-peptide |
Purinergic |
P2Y6 |
1321N1/P2Y6 |
M00346 |
A |
Non-peptide |
Purinergic |
P2Y11 |
1321N1/P2Y11 |
M00298 |
A |
Non-peptide |
Purinergic |
P2Y12 |
1321N1/P2Y12/Gα15 |
M00261 |
A |
Non-peptide |
Serotonin |
5-HT1A / HTR1A |
CHO-K1/5-HT1A/Gα15 |
M00330 |
A |
Non-peptide |
Serotonin |
5-HT2A / HTR2A |
CHO-K1/5-HT2A |
M00251 |
A |
Non-peptide |
Serotonin |
5-HT2B / HTR2B |
CHO-K1/5-HT2B |
M00249 |
A |
Non-peptide |
Serotonin |
5-HT2C / HTR2C |
CHO-K1/5-HT2C |
M00253 |
A |
Non-peptide |
Serotonin |
5-HT2C / HTR2C |
HEK293/5-HT2C |
M00319 |
A |
Non-peptide |
Serotonin |
5-HT4 / HTR4 |
CHO-K1/5-HT4/Gα15 |
M00444 |
A |
Non-peptide |
Serotonin |
5-HT7 / HTR7 |
293/5-HT7/CRE-Luc |
M00423 |
A |
Peptide |
Somatostatin |
SST1 |
CHO-K1/SST1/Gqi5 |
M00473 |
A |
Peptide |
Somatostatin |
SST2 |
CHO-K1/SST2/Gα15 |
M00325 |
A |
Peptide |
Somatostatin |
SST3 |
CHO-K1/SST3/Gα15 |
M00285 |
A |
Peptide |
Somatostatin |
SST4 |
CHO-K1/SST4/Gα15 |
M00334 |
A |
Peptide |
Somatostatin |
SST5 |
CHO-K1/SST5/Gα15 |
M00286 |
A |
Peptide |
Tachykinin |
NK1 / TACR1 |
CHO-K1/NK1 |
M00199 |
A |
Peptide |
Tachykinin |
NK2 / TACR2 |
CHO-K1/NK2 |
M00200 |
A |
Peptide |
Tachykinin |
NK3 / TACR3 |
CHO-K1/NK3 |
M00201 |
A |
Peptide |
Thyrtropin-releasing Hormone |
TRH1 |
CHO-K1/TRH1 |
M00202 |
A |
Peptide |
Urotensin |
UT2 |
CHO-K1/UT2/Gα15 |
M00339 |
A |
Peptide |
Vasopressin |
V1A / AVPR1A |
CHO-K1/V1A |
M00181 |
A |
Peptide |
Vasopressin |
V1B / AVPR1B |
CHO-K1/V1B |
M00205 |
A |
Peptide |
Vasopressin |
V2 / AVPR2 |
CHO-K1/V2/Gα15 |
M00170 |
A |
|
Orphan |
GPR120 |
CHO-K1/GPR120/Gα15 |
M00440 |
A |
|
Orphan |
MRGD / MRGPRD |
CHO-K1/MRGPRD/Gα15 |
M00467 |
A |
|
Orphan |
MRGX2 / MRGPRX2 |
CHO-K1/MRGPRX2 |
M00425 |
A |
|
Orphan |
OXGR1 |
CHO-K1/OXGR1/Gα15 |
M00483 |
A |
|
Orphan |
P2Y5 |
RH7777/P2Y5 |
M00472 |
A |
|
Orphan |
SUCNR1 / GPR91 |
CHO-K1/SUCNR1/Gα15 |
M00471 |
B |
Peptide |
Calcitonin |
CALCR / CT |
CHO-K1/CT/Gα15 |
M00320 |
B |
Peptide |
Calcitonin |
AMY1 (RAMP1 + CALCR) |
CHO-K1/AMY1/CRE-Luc |
M00350 |
B |
Peptide |
Calcitonin |
AMY1 (RAMP1 + CALCR) |
CHO-K1/AMY1/Gα15 |
M00475 |
B |
Peptide |
Calcitonin |
AMY2 (RAMP2 + CALCR) |
CHO-K1/AMY2/Gα15 |
M00478 |
B |
Peptide |
Calcitonin |
AMY3 (RAMP3 + CALCR) |
CHO-K1/AMY3/Gα15 |
M00481 |
B |
Peptide |
Calcitonin |
AM1 (RAMP2 + CALCRL) |
CHO-K1/AM1 |
M00450 |
B |
Peptide |
Calcitonin |
AM2 (RAMP3 + CALCRL) |
CHO-K1/AM2/Gα15 |
M00479 |
B |
Peptide |
Corticotropin Releasing Factor |
CRF1 |
CHO-K1/CRF1/Gα15 |
M00343 |
B |
Peptide |
Corticotropin Releasing Factor |
CRF2 |
CHO-K1/CRF2/Gα15 |
M00208 |
B |
Peptide |
Glucagon |
GCGR |
CHO-K1/GCGR/Gα15 |
M00345 |
B |
Peptide |
Glucagon |
GCGR |
HEK293/GCGR/Gα15 |
M00422 |
B |
Peptide |
Glucagon |
GHRH |
293/GHRH/Gα15 |
M00314 |
B |
Peptide |
Glucagon |
GIP |
CHO-K1/GIP/Gα15 |
M00486 |
B |
Peptide |
Glucagon |
GLP1 |
CHO-K1/GLP1/Gα15 |
M00451 |
B |
Peptide |
Glucagon |
GLP2 |
CHO-K1/GLP2/Gα15 |
M00307 |
B |
Peptide |
Glucagon |
SCTR |
CHO-K1/SCTR/Gα15 |
M00326 |
B |
Peptide |
Parathyroid Hormone |
PTH1 |
CHO-K1/PTH1/Gα15 |
M00315 |
B |
Peptide |
Parathyroid Hormone |
PTH2 |
293/PTH2/CRE-Luc |
M00270 |
B |
Peptide |
VIP / PACAP |
PAC1 |
CHO-K1/PAC1/Gα15 |
M00203 |
B |
Peptide |
VIP / PACAP |
VPAC1 |
CHO-K1/VPAC1/Gα15 |
M00342 |
B |
Peptide |
VIP / PACAP |
VPAC2 |
CHO-K1/VPAC2/Gα15 |
M00226 |
C |
Non-peptide |
Calcium-sensor |
CASR |
CHO-K1/CASR |
M00434 |
C |
Non-peptide |
Glutamate |
mGlu2 / GRM2 |
CHO-K1/GRM2/Gα15 |
M00427 |
| |
|
Control |
|
CHO-K1/CRE-Luc |
M00187 |
| |
|
Control |
|
293/CRE-Luc |
M00188 |
| |
|
Control |
|
CHO-K1/Gα15 |
M00257 |
| |
|
Control |
|
CHO-K1/Gqi5 |
M00455 |
