IL-1 beta Antibody (6B1G11), mAb, Mouse

Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which subsequently proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes. It is also released from several other cell types and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin1 alpha (IL1 alpha) and interleukin1 beta (IL1 beta), not only bind to the same cell surface receptor and elicit nearly identical biological responses but also share 25% homology in their amino acid sequence.