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CXCR2 Antibody, pAb, Rabbit

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CXCR2 is a member of the GPCR family (subfamily, chemokine). It is a receptor for Interleukin 8 (IL8), which is a powerful neutrophil chemotactic factor. Binding of IL8 with the receptor activates neutrophils. This response is mediated by a second messenger system in which G-protein activates phosphatidyl inositol-calcium. This receptor binds to IL8, GRO/MGSA, and NAP2 with a high affinity. Its expression has been reported to be in a wide variety of tissues.GenScript Rabbit Anti-CXCR2 Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide derived from N-terminal extracellular domain of human CXCR2.
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Specificity GenScript Rabbit Anti-CXCR2 Polyclonal Antibody detects human CXCR2 protein. It has not yet been tested for other species.
Host Species Rabbit
Immunogen KLH-coupled synthetic peptide derived from N-terminal extracellular domain of human CXCR2.

Concentration 0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide
Reconstitution Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.
Purification Immunoaffinity chromatography

Target Background CXCR2 is a member of the GPCR family (subfamily, chemokine). It is a receptor for Interleukin 8 (IL8), which is a powerful neutrophil chemotactic factor. Binding of IL8 with the receptor activates neutrophils. This response is mediated by a second messenger system in which G-protein activates phosphatidyl inositol-calcium. This receptor binds to IL8, GRO/MGSA, and NAP2 with a high affinity. Its expression has been reported to be in a wide variety of tissues.
GenScript Rabbit Anti-CXCR2 Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide derived from N-terminal extracellular domain of human CXCR2.
Synonyms Rabbit Anti-CXCR2 pAb;

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